Curcumin has been shown to be of use in reversing many steps in the pathological process of heart disease. Possibly the chief advantage of curcumin when it comes to heart illness is improving the role of the endothelium, which is the lining of the blood vessels. It is well known that endothelial dysfunction is a main driver of heart illness and includes an inability of the endothelium to regulate blood pressure, blood clotting and various other factors.